Notes on Skeletal muscle contraction, Neuron and kinds of Neuron and Importance of Spinal Cord
Skeletal muscle contraction:
Electron
microscopy and biochemical analysis show that in muscle fibres cell bends are
due to the placement of muscle protein action and myosin with myofibrils.
Myosin occurs as thick filaments and actin as thin filaments. The lightest
region of a myofibril contains only actin whereas the darkest region contains
both.
The functional
(contractile) unit of a myofibril is sarcomere each of which extends from one Z
line to another z line. The actin filaments attach to the Z lines whereas
myosin filaments do not.
When a sarcomere
contracts the actin filament slide pas the myosin filaments as they approach
one another. This process shortens the sarcomere. The combined decreases in
length of the individual sarcomeres account for contraction of the whole muscle
fibres and in turn, the whole muscle.
A ratchet
mechanism between two filament types produces the actual contraction. Myosin
contains globular projections that attach to actin as specific active binding
sites, forming attachments called cross bridges. Once cross bridges form, they
exert a force on thin actin filament and cause it to move.
Neuron and kinds of Neuron:
Neuron is
functional unit of nervous system. Neurons are specialized to produce signals
that can be communicated over short to long distances from one part of animals’
body to another. There are three neurons.
(1) Sensory
neurons (receptor or afferent): Either act as receptors of stimuli themselves
or are activated by receptors. Changes in the internal or external environments
stimulate sensory nervous which respond by sending signals to the major
integrating centers where information is processed.
(2) Inter
neurons: It comprise the integrating centres and receive signals from sensory
neurons and transmit them to motor neurons.
(3) Motor
neurons (effector or efferent): It sends the processed information via a signal
to the body’s effector muscles, causing them to contract or to glands causing
them to secret.
Importance of Spinal Cord:
Spinal cord is
the part of central nervous system that extends from the brain to near of into
the tail. A cross section shows a neural canal that contains cerebro spinal
fluid. The grey matter consists of cell bodies and dendrites and is concerned
with reflex connections at various levels of spinal cord. Extending from spinal
cord are ventral and dorsal roots of spinal nerves. These roots contain main
motor and sensory fibres (axon or dendrites) that contribute to the major
spinal nerves. White matter of spinal cord gets its name from the whitish
myelin that covers it.
Function: Spinal
cord is link between brain and most of body parts and is involved in reflex
actions.
A reflex is
predictable involuntary response to a stimulus. Thus both voluntary and
involuntary limb movements, as well as certain organ functions depend on this
link.
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